human CDH10 shRNA silencing Adenovirus

Name
Ad-h-CDH10-shRNA

Cat No
shADV-204803

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CDH10.

shADV-204803

Ad-h-CDH10-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CDH10 (cadherin 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

CDH10 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

Gene ID

1008

Gene Name (Vector)

cadherin 10

Gene Symbol

CDH10

HGNC ID

HGNC:1749

ORF Size (aa)

2364

ORF Size (bp)

2364 bp

RefSeq ID

NM_006727

RefSeq Synonyms

NM_006727, NM_001317224, NM_001317222, BC156818, BC152828,

Species

human

UniGene ID

Hs.92489

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.