human CDC25B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CDC25B.
shADV-204738
Ad-h-CDC25B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CDC25B (cell division cycle 25B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Gene ID
994
Gene Name (Vector)
cell division cycle 25B
Gene Symbol
CDC25B
HGNC ID
HGNC:1726
ORF Size (aa)
1743
ORF Size (bp)
1743 bp
RefSeq ID
NM_004358
RefSeq Synonyms
NM_021873, NM_021872, NM_004358, NM_001287524, NM_001287522, NM_001287520, NM_001287519, NM_001287518, NM_001287517, NM_001287516, BC051711, BC009953, BC006395,
Species
human
UniGene ID
Hs.153752
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.