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human CDA shRNA silencing Adenovirus

Name 
Ad-h-CDA-shRNA
Cat No 
shADV-204709
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CDA.

shADV-204709
Ad-h-CDA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CDA (cytidine deaminase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CDD
Description (Vector)
CDA encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
Gene ID
978
Gene Name (Vector)
cytidine deaminase
Gene Symbol
CDA
HGNC ID
HGNC:1712
ORF Size (aa)
441
ORF Size (bp)
441 bp
RefSeq ID
NM_001785
RefSeq Synonyms
NM_001785, BC054036,
Species
human
UniGene ID
Hs.466910

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.