human CD8B shRNA silencing Adenovirus

Name 
Ad-h-CD8B-shRNA
Cat No 
shADV-204697
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CD8B.

shADV-204697
Ad-h-CD8B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD8B (CD8b molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD8B1; LEU2; LY3; LYT3; MGC119115; P37;
Description (Vector)
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Gene ID
926
Gene Name (Vector)
CD8b molecule
Gene Symbol
CD8B
HGNC ID
HGNC:1707
ORF Size (aa)
597
RefSeq ID
NM_004931
RefSeq Synonyms
NM_172213, NM_172102, NM_172101, NM_004931, NM_001178100, BC100914, BC100913, BC100912, BC100911,
Species
human
UniGene ID
Hs.405667

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.