human CD28 shRNA silencing Adenovirus

Name 
Ad-h-CD28-shRNA
Cat No 
shADV-204623
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CD28.

shADV-204623
Ad-h-CD28-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD28 (CD28 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD antigen CD28; CD28 antigen; T-cell-specific surface glycoprotein CD28; Tp44
Description (eCommerce)
CD28 is involved in T-cell activation, the induction of cell proliferation and cytokine production, and promotion of T-cell survival [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P10747].
Description (Vector)
CD28 is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
940
Gene Name (eCommerce)
CD28 molecule
Gene Name (Vector)
CD28 molecule
Gene Symbol
CD28
HGNC ID
HGNC:1653
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
663
ORF Size (bp)
663 bp
Protein Name (eCommerce)
T-cell-specific surface glycoprotein CD28
RefSeq ID
NM_006139
RefSeq Synonyms
NM_006139, NM_001243078, NM_001243077, BC112085, BC093698,
Research Areas
B-cell Receptor Signaling,Cancer,Cardiology,Cardiovascular,Cell Cycle,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,Host-Virus Interactions,Immunology,Innate Immunity,Interleukin Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling,Translational Control
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,genetics,immunology,infectious_disease,neurobiology,signal_transduction,stem_cell_biology,transcription_translation
Species
human
Target Sentence
CD28 is involved in T-cell activation, the induction of cell proliferation and cytokine production, and promotion of T-cell survival [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P10747].
UniGene ID
Hs.591629
UniProt ID (eCommerce)
P10747

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.