human CD226 shRNA silencing Adenovirus

Name 
Ad-h-CD226-shRNA
Cat No 
shADV-204609
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CD226.

shADV-204609
Ad-h-CD226-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD226 (CD226 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
adhesion glycoprotein; CD antigen CD226; CD226 antigen; DNAM1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; PTA1; T lineage-specific activation antigen 1 antigen; TLiSA1
Description (eCommerce)
DNAX accessory molecule-1 (DNAM-1) is a receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15762].
Description (Vector)
CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.
Gene ID
10666
Gene Name (eCommerce)
CD226 molecule
Gene Name (Vector)
CD226 molecule
Gene Symbol
CD226
HGNC ID
HGNC:16961
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1011
ORF Size (bp)
1011 bp
Protein Name (eCommerce)
CD226 antigen
RefSeq ID
NM_006566
RefSeq Synonyms
NM_006566, NM_001303619, NM_001303618, BC074787,
Research Areas
Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
DNAX accessory molecule-1 (DNAM-1) is a receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15762].
UniGene ID
Hs.660130
UniProt ID (eCommerce)
Q15762

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.