human CD22 shRNA silencing Adenovirus

Name 
Ad-h-CD22-shRNA
Cat No 
shADV-204608
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CD22.

shADV-204608
Ad-h-CD22-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD22 (CD22 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD antigen CD22; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14
Description (eCommerce)
CD22 mediates B-cell B-cell interactions and is involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins including CD45. It is involved in B cell activation; negative regulation of the B cell receptor signaling pathway; and regulation of endocytosis. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P20273].
Gene ID
933
Gene Name (eCommerce)
CD22 molecule
Gene Name (Vector)
CD22 molecule
Gene Symbol
CD22
HGNC ID
HGNC:1643
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2028
ORF Size (bp)
2028 bp
Protein Name (eCommerce)
B-cell receptor CD22
RefSeq ID
NM_001771
RefSeq Synonyms
NM_001771, NM_001278417, NM_001185101, NM_001185100, NM_001185099, BC109306,
Research Areas
B-cell Receptor Signaling,Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
CD22 mediates B-cell B-cell interactions and is involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins including CD45. It is involved in B cell activation; negative regulation of the B cell receptor signaling pathway; and regulation of endocytosis. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P20273].
UniGene ID
Hs.579691
UniProt ID (eCommerce)
P20273

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.