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human CD1E shRNA silencing Adenovirus

Name 
Ad-h-CD1E-shRNA
Cat No 
shADV-204597
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CD1E.

shADV-204597
Ad-h-CD1E-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD1E (CD1e molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD1A; R2
Description (Vector)
CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined.
Gene ID
913
Gene Name (Vector)
CD1e molecule
Gene Symbol
CD1E
HGNC ID
HGNC:1638
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
RefSeq ID
NM_030893
RefSeq Synonyms
NM_030893, NM_001185115, NM_001185114, NM_001185113, NM_001185112, NM_001185110, NM_001185108, NM_001185107, NM_001042587, NM_001042586, NM_001042585, NM_001042584, NM_001042583, BC131693,
Species
human
UniGene ID
Hs.249217

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.