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human CD1D shRNA silencing Adenovirus

Name 
Ad-h-CD1D-shRNA
Cat No 
shADV-204596
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CD1D.

shADV-204596
Ad-h-CD1D-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD1D (CD1d molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
antigen-presenting glycoprotein CD1d; CD antigen CD1d; CD1A; CD1D antigen, d polypeptide; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D; R3; R3G1; T-cell surface glycoprotein CD1d; thymocyte antigen CD1D
Description (eCommerce)
CD1D is an antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells [taken from NCBI Entrez Gene (Gene ID: 912)].
Description (Vector)
CD1D encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.
Gene ID
912
Gene Name (eCommerce)
CD1d molecule
Gene Name (Vector)
CD1d molecule
Gene Symbol
CD1D
HGNC ID
HGNC:1637
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1008
ORF Size (bp)
1008 bp
Protein Name (eCommerce)
Antigen-presenting glycoprotein CD1d
RefSeq ID
NM_001766
RefSeq Synonyms
NM_001766, NM_001319145, BC027926,
Research Areas
Antigen Processing and Presentation,Host-Virus Interactions,Immunology,Innate Immunity,Lysosome,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology,infectious_disease,immunology,cell_biology
Species
human
Target Sentence
CD1D is an antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells [taken from NCBI Entrez Gene (Gene ID: 912)].
UniGene ID
Hs.1799
UniProt ID (eCommerce)
P15813

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.