human CCR7 shRNA silencing Adenovirus

Name 
Ad-h-CCR7-shRNA
Cat No 
shADV-204544
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CCR7.

shADV-204544
Ad-h-CCR7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CCR7 (C-C motif chemokine receptor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1
Description (Vector)
CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
Gene ID
1236
Gene Name (Vector)
C-C motif chemokine receptor 7
Gene Symbol
CCR7
HGNC ID
HGNC:1608
ORF Size (aa)
1137
ORF Size (bp)
1137 bp
RefSeq ID
NM_001838
RefSeq Synonyms
NM_001838, NM_001301718, NM_001301717, NM_001301716, NM_001301714, BC035343,
Species
human
UniGene ID
Hs.370036

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.