human CCNE2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CCNE2.
shADV-204496
Ad-h-CCNE2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CCNE2 (cyclin E2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CYCE2; G1/S-specific cyclin-E2
Description (eCommerce)
Cyclin E2 is essential for the control of the cell cycle at the late G1 and early S phase  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O96020].
Description (Vector)
CCNE2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.
Gene ID
9134
Gene Name (eCommerce)
cyclin E2
Gene Name (Vector)
cyclin E2
Gene Symbol
CCNE2
HGNC ID
HGNC:1590
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
891
ORF Size (bp)
891 bp
Protein Name (eCommerce)
G1/S-specific cyclin-E2
RefSeq ID
NM_057749
RefSeq Synonyms
NM_057749, BC020729, BC007015,
Research Areas
Cancer,Cell Cycle,Cell Division,DNA Damage/Repair,Host-Virus Interactions,Lung Cancer,Meiosis,Neurobiology,Neurodegeneration,p53 Signaling,Parkinson's Disease,PI3K/Akt Signaling,Prostate Cancer,Signal Transduction,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,infectious_disease,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Cyclin E2 is essential for the control of the cell cycle at the late G1 and early S phase  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O96020].
UniGene ID
Hs.567387
UniProt ID (eCommerce)
O96020
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.