human CCL22 shRNA silencing Adenovirus

Name 
Ad-h-CCL22-shRNA
Cat No 
shADV-204433
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CCL22.

shADV-204433
Ad-h-CCL22-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CCL22 (C-C motif chemokine ligand 22). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
A-152E5.1; ABCD-1; DC/B-CK; MDC; SCYA22; STCP-1
Description (Vector)
CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
Gene ID
6367
Gene Name (Vector)
C-C motif chemokine ligand 22
Gene Symbol
CCL22
HGNC ID
HGNC:10621
ORF Size (aa)
282
RefSeq ID
NM_002990
RefSeq Synonyms
NM_002990, BC027952,
Species
human
UniGene ID
Hs.534347

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.