human CBX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CBX1.
shADV-204194
Ad-h-CBX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CBX1 (chromobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CBX; HP1-BETA; HP1Hs-beta; HP1Hsbeta; M31; MOD1; p25beta
Description (Vector)
CBX1 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
10951
Gene Name (Vector)
chromobox 1
Gene Symbol
CBX1
HGNC ID
HGNC:1551
ORF Size (aa)
558
ORF Size (bp)
558 bp
RefSeq ID
NM_006807
RefSeq Synonyms
NM_006807, NM_001127228, BC021302, BC002609,
Species
human
UniGene ID
Hs.77254
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.