human CBS shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-204180
Availability:
3-5 weeks
Name:
Ad-h-CBS-shRNA
This is an Adenovirus expressing shRNA for silencing of Human CBS.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CBS
- Gene Name
- cystathionine-beta-synthase
- Gene ID
- 875
- Gene Synonyms
- HIP4
- ORF Size
- 1656 bp
- RefSeq#
- NM_000071
- Gene Description
- CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.
- UniGene ID
- Hs.533013
- HGNC ID
- HGNC:1550
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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