human CBLC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CBLC.
shADV-204164
Ad-h-CBLC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CBLC (Cbl proto-oncogene C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cas-Br-M (murine) ecotropic retroviral transforming sequence c; Cas-Br-M (murine) ectropic retroviral transforming sequence c; Cbl proto-oncogene C, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase C; CBL-3; CBL-SL; E3 ubiquitin-protein ligase CBL-C; RING finger protein 57; RING-type E3 ubiquitin transferase CBL-C; RNF57; SH3-binding protein CBL-3; SH3-binding protein CBL-C; signal transduction protein CBL-C
Description (eCommerce)
CBLC is a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases [taken from NCBI Entrez Gene (Gene ID: 23624)].
Description (Vector)
CBLC encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
23624
Gene Name (eCommerce)
Cbl proto-oncogene C
Gene Name (Vector)
Cbl proto-oncogene C
Gene Symbol
CBLC
HGNC ID
HGNC:15961
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1425
ORF Size (bp)
1425 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase CBL-C
RefSeq ID
NM_012116
RefSeq Synonyms
NM_012116, NM_001130852, BC028915,
Research Areas
Cancer,EGFR Signaling,GPCR Signaling,Immunology,Insulin Signaling,JAK-STAT Signaling,Leukemia,Signal Transduction,T-cell Receptor Signaling,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,immunology,signal_transduction
Species
human
Target Sentence
CBLC is a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases [taken from NCBI Entrez Gene (Gene ID: 23624)].
UniGene ID
Hs.466907
UniProt ID (eCommerce)
Q9ULV8
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.