human CASQ2 shRNA silencing Adenovirus

Name
Ad-h-CASQ2-shRNA

Cat No
shADV-204130

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CASQ2.

shADV-204130

Ad-h-CASQ2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CASQ2 (calsequestrin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

PDIB2

Description (Vector)

CASQ2 specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Gene ID

845

Gene Name (Vector)

calsequestrin 2

Gene Symbol

CASQ2

HGNC ID

HGNC:1513

ORF Size (aa)

1200

ORF Size (bp)

1200 bp

RefSeq ID

NM_001232

RefSeq Synonyms

NM_001232, BC022288,

Species

human

UniGene ID

Hs.57975

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.