human CAPZB shRNA silencing Adenovirus

Name 
Ad-h-CAPZB-shRNA
Cat No 
shADV-204075
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CAPZB.

shADV-204075
Ad-h-CAPZB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CAPZB (capping actin protein of muscle Z-line beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAPB; CAPPB; capping actin protein of muscle Z-line beta subunit; capping protein (actin filament) muscle Z-line, beta; CAP; ZcapZ beta; epididymis secretory sperm binding protein; F-actin-capping protein subunit beta
Description (eCommerce)
CAPZB is the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells [taken from NCBI Entrez Gene (Gene ID: 832)].
Description (Vector)
CAPZB encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Gene ID
832
Gene Name (eCommerce)
capping actin protein of muscle Z-line subunit beta
Gene Name (Vector)
capping actin protein of muscle Z-line beta subunit
Gene Symbol
CAPZB
HGNC ID
HGNC:1491
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
819
ORF Size (bp)
819 bp
Protein Name (eCommerce)
F-actin-capping protein subunit beta
RefSeq ID
NM_004930
RefSeq Synonyms
NM_004930, NM_001313932, NM_001282162, NM_001206541, NM_001206540, BC109242, BC109241, BC107752,
Research Areas
Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
CAPZB is the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells [taken from NCBI Entrez Gene (Gene ID: 832)].
UniGene ID
Hs.432760
UniProt ID (eCommerce)
P47756

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.