human CACYBP shRNA silencing Adenovirus

Name 
Ad-h-CACYBP-shRNA
Cat No 
shADV-203931
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CACYBP.

shADV-203931
Ad-h-CACYBP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CACYBP (calcyclin binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CacyBP; calcyclin-binding protein; GIG5; growth-inhibiting gene 5 protein; hCacyBP; PNAS-107; S100A6-binding protein; S100A6BP; Siah-interacting protein; Siah-interacting protein (SIP); SIP
Description (eCommerce)
Calcyclin binding protein (CacyBP) is a protein that binds calcyclin. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin [taken from NCBI Entrez Gene (Gene ID: 27101].
Description (Vector)
CACYBP is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
27101
Gene Name (eCommerce)
calcyclin binding protein
Gene Name (Vector)
calcyclin binding protein
Gene Symbol
CACYBP
HGNC ID
HGNC:30423
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
687
ORF Size (bp)
687 bp
Protein Name (eCommerce)
Calcyclin-binding protein
RefSeq ID
NM_014412
RefSeq Synonyms
NM_014412, NM_001007214, BC078151, BC067823, BC022352, BC005975,
Research Areas
Aging,Apoptosis,Cancer,Cardiac Development,Cardiology,Cardiovascular,DNA Replication,Neurobiology,Signal Transduction,Ubiquitination,Wnt Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,genetics,transcription_translation,neurobiology,signal_transduction
Species
human
Target Sentence
Calcyclin binding protein (CacyBP) is a protein that binds calcyclin. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin [taken from NCBI Entrez Gene (Gene ID: 27101].
UniGene ID
Hs.508524
UniProt ID (eCommerce)
Q9HB71

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.