human CABC1 shRNA silencing Adenovirus

Name
Ad-h-CABC1-shRNA

Cat No
shADV-203890

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human COQ8A.

shADV-203890

Ad-h-CABC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human COQ8A (coenzyme Q8A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ADCK3; ARCA2; CABC1; COQ10D4; COQ8; SCAR9

Description (Vector)

ADCK3 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.

Gene ID

56997

Gene Name (Vector)

coenzyme Q8A

Gene Symbol

COQ8A

HGNC ID

HGNC:16812

ORF Size (aa)

1944

ORF Size (bp)

1944 bp

RefSeq ID

NM_020247

RefSeq Synonyms

NM_020247, BC129930, BC005171,

Species

human

UniGene ID

Hs.118241

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.