human C9ORF72 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human C9orf72.
shADV-203838
Ad-h-C9ORF72-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human C9orf72 (chromosome 9 open reading frame 72). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALSFTD; DENNL72; FTDALS; FTDALS1
Description (Vector)
Expansion of a hexanucleotide repeat in non-coding sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
203228
Gene Name (Vector)
chromosome 9 open reading frame 72
Gene Symbol
C9orf72
HGNC ID
HGNC:28337
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
RefSeq ID
NM_018325
RefSeq Synonyms
NM_145005, NM_018325, NM_001256054, BC068445,
Species
human
UniGene ID
Hs.493639
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.