human C7ORF11 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MPLKIP

Gene Name

M-phase specific PLK1 interacting protein

Gene ID

136647

Gene Synonyms

ABHS; C7orf11; ORF20; TTD4

ORF Size

540 bp

RefSeq#

NM_138701

Gene Description

MPLKIP localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.

UniGene ID

Hs.654989

HGNC ID

HGNC:16002