human BACH1 shRNA silencing Adenovirus

Name 
Ad-h-BACH1-shRNA
Cat No 
shADV-203228
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human BACH1.

shADV-203228
Ad-h-BACH1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BACH1 (BTB domain and CNC homolog 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BACH-1; basic region leucine zipper transcriptional regulator BACH1; BTB and CNC homolog 1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; BTBD24; HA2303; transcription regulator protein BACH1
Description (eCommerce)
BACH1 (BTB and CNC homolog1) is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). BACH1 contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. BACH1 can form heterodimers with MafK to function as a repressor of transcription.
Description (Vector)
BACH1 encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.
Gene ID
571
Gene Name (eCommerce)
BTB domain and CNC homolog 1
Gene Name (Vector)
BTB domain and CNC homolog 1
Gene Symbol
BACH1
HGNC ID
HGNC:935
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2211
ORF Size (bp)
2211 bp
Protein Name (eCommerce)
Transcription regulator protein BACH1
RefSeq ID
NM_001186
RefSeq Synonyms
NM_206866, NM_001186, BC063307,
Research Areas
Breast Cancer,Cancer,Cell Cycle,Immunology,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,immunology,genetics,transcription_translation
Species
human
Target Sentence
BACH1 (BTB and CNC homolog1) is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). BACH1 contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. BACH1 can form heterodimers with MafK to function as a repressor of transcription.
UniGene ID
Hs.154276
UniProt ID (eCommerce)
O14867

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.