human C1ORF57 shRNA silencing Adenovirus

Name 
Ad-h-C1ORF57-shRNA
Cat No 
shADV-203089
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NTPCR.

shADV-203089
Ad-h-C1ORF57-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NTPCR (nucleoside-triphosphatase, cancer-related). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C1orf57; cancer-related nucleoside-triphosphatase; HCR-NTPase; human cancer-related NTPase; NTPase; nucleoside triphosphate phosphohydrolase; nucleoside-triphosphatase C1orf57
Description (eCommerce)
Nucleoside triphosphate phosphohydrolase (NTPCR) is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This protein is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. It has been found that cytotoxicity is not related to its triphosphatase activity [taken from NCBI Entrez Gene (Gene ID: 84284)].
Gene ID
84284
Gene Name (eCommerce)
nucleoside-triphosphatase, cancer-related
Gene Name (Vector)
nucleoside-triphosphatase, cancer-related
Gene Symbol
NTPCR
HGNC ID
HGNC:28204
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
573
ORF Size (bp)
573 bp
Protein Name (eCommerce)
Cancer-related nucleoside-triphosphatase
RefSeq ID
NM_032324
RefSeq Synonyms
NM_032324, NM_001329453, NM_001329452, BC005102,
Research Areas
Cell Biology,Metabolism/Metabolic Process,Phosphatase
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Nucleoside triphosphate phosphohydrolase (NTPCR) is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This protein is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. It has been found that cytotoxicity is not related to its triphosphatase activity [taken from NCBI Entrez Gene (Gene ID: 84284)].
UniGene ID
Hs.642715
UniProt ID (eCommerce)
Q9BSD7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.