human C10ORF4 shRNA silencing Adenovirus

Name 
Ad-h-C10ORF4-shRNA
Cat No 
shADV-202423
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human FRA10AC1.

shADV-202423
Ad-h-C10ORF4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FRA10AC1 (FRA10A associated CGG repeat 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C10orf4; F26C11.1-like; FRA10A; fragile site 10q23.3; fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1; protein FRA10AC1; rare folic acid-type fragile site, FRA(10)(q23.3), candidate gene 1
Description (eCommerce)
FRA10AC1 [fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1] is ubiquitously expressed with higher expression in brain, heart, skeletal muscle, kidney and liver [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q70Z53].
Description (Vector)
FRA10AC1 is a nuclear phosphoprotein of unknown function. The 5' UTR of this gene is part of a CpG island and contains a tandem CGG repeat region that normally consists of 8-14 repeats but can expand to over 200 repeats. The expanded allele becomes hypermethylated and is not transcribed; however, an expanded repeat region has not been associated with any disease phenotype. This gene is found within the rare FRA10A folate-sensitive fragile site.
Gene ID
118924
Gene Name (eCommerce)
FRA10A associated CGG repeat 1
Gene Name (Vector)
FRA10A associated CGG repeat 1
Gene Symbol
FRA10AC1
HGNC ID
HGNC:1162
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
948
ORF Size (bp)
948 bp
Protein Name (eCommerce)
Protein FRA10AC1
RefSeq ID
NM_145246
RefSeq Synonyms
NM_145246, BC018007,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
FRA10AC1 [fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1] is ubiquitously expressed with higher expression in brain, heart, skeletal muscle, kidney and liver [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q70Z53].
UniGene ID
Hs.658192
UniProt ID (eCommerce)
Q70Z53

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.