human BRMS1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BRMS1.
shADV-202273
Ad-h-BRMS1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BRMS1 (breast cancer metastasis suppressor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Gene ID
25855
Gene Name (Vector)
breast cancer metastasis suppressor 1
Gene Symbol
BRMS1
HGNC ID
HGNC:17262
ORF Size (aa)
741
ORF Size (bp)
741 bp
RefSeq ID
NM_015399
RefSeq Synonyms
NM_015399, NM_001024957, BC009834,
Species
human
UniGene ID
Hs.100426
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.