human BMF shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BMF.
shADV-202176
Ad-h-BMF-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BMF (Bcl2 modifying factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
BMF belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
90427
Gene Name (Vector)
Bcl2 modifying factor
Gene Symbol
BMF
HGNC ID
HGNC:24132
ORF Size (aa)
555
ORF Size (bp)
555 bp
RefSeq ID
NM_033503
RefSeq Synonyms
NM_033503, NM_001003943, NM_001003942, NM_001003940, BC104985, BC104983, BC070043, BC069505, BC069328,
Species
human
UniGene ID
Hs.591104
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.