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human ATP5S shRNA silencing Adenovirus

Name 
Ad-h-ATP5S-shRNA
Cat No 
shADV-201736
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ATP5S.

shADV-201736
Ad-h-ATP5S-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ATP5S (ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATPW; FB; HSU79253
Description (Vector)
ATP5S encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. ATP5S encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
27109
Gene Name (Vector)
ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)
Gene Symbol
ATP5S
HGNC ID
HGNC:18799
ORF Size (aa)
384
ORF Size (bp)
384 bp
RefSeq ID
NM_015684
RefSeq Synonyms
NM_015684, NM_001003805, NM_001003803, BC011549,
Species
human
UniGene ID
Hs.438489

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.