human ATP5G3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ATP5G3.
shADV-201724
Ad-h-ATP5G3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ATP5G3 (ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
P3
Description (Vector)
ATP5G3 encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). ATP5G3 is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified.
Gene ID
518
Gene Name (Vector)
ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9)
Gene Symbol
ATP5G3
HGNC ID
HGNC:843
ORF Size (aa)
429
ORF Size (bp)
429 bp
RefSeq ID
NM_001689
RefSeq Synonyms
NM_001689, NM_001190329, NM_001002258, BC106881,
Species
human
UniGene ID
Hs.429
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.