human ATP1A4 shRNA silencing Adenovirus

Name
Ad-h-ATP1A4-shRNA

Cat No
shADV-201684

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ATP1A4.

shADV-201684

Ad-h-ATP1A4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ATP1A4 (ATPase Na+/K+ transporting subunit alpha 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ATP1A1; ATP1AL2

Description (Vector)

ATP1A4 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

480

Gene Name (Vector)

ATPase Na+/K+ transporting subunit alpha 4

Gene Symbol

ATP1A4

HGNC ID

HGNC:14073

ORF Size (aa)

3090

ORF Size (bp)

3090 bp

RefSeq ID

NM_144699

RefSeq Synonyms

NM_144699, NM_001001734, BC094801, BC028297,

Species

human

UniGene ID

Hs.662219

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.