human ATL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ATL1.
shADV-201652
Ad-h-ATL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ATL1 (atlastin GTPase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AD-FSP; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
Description (Vector)
ATL1 is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
51062
Gene Name (Vector)
atlastin GTPase 1
Gene Symbol
ATL1
HGNC ID
HGNC:11231
ORF Size (aa)
1677
ORF Size (bp)
1677 bp
RefSeq ID
NM_015915
RefSeq Synonyms
NM_181598, NM_015915, NM_001127713, BC010708,
Species
human
UniGene ID
Hs.584905
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.