human ASH1L shRNA silencing Adenovirus

Name 
Ad-h-ASH1L-shRNA
Cat No 
shADV-201555
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ASH1L.

shADV-201555
Ad-h-ASH1L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ASH1L (ASH1 like histone lysine methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
absent small and homeotic disks protein 1 homolog; ASH1; ash1 (absent, small, or homeotic)-like; ASH1L1; ASH1-like protein; histone-lysine N-methyltransferase ASH1L; huASH1; KMT2H; lysine N-methyltransferase 2H; MRD52; probable histone-lysine N-methyltransferase ASH1L
Description (eCommerce)
ASH1 (absent small and homeotic disks protein 1 homolog) is a member of the trithorax group of transcriptional activators. ASH1 exhibits histone methyltransferase activity and has been observed to associate with the transcribed region of most active genes.
Description (Vector)
ASH1L encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions.
Gene ID
55870
Gene Name (eCommerce)
ASH1 like histone lysine methyltransferase
Gene Name (Vector)
ASH1 like histone lysine methyltransferase
Gene Symbol
ASH1L
HGNC ID
HGNC:19088
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
8895
ORF Size (bp)
8895 bp
Protein Name (eCommerce)
Histone-lysine N-methyltransferase ASH1L
RefSeq ID
NM_018489
RefSeq Synonyms
NM_018489, BC172595,
Research Areas
Chromatin Remodeling,Golgi Apparatus,Histone Modification,Methyltransferase,Neurobiology,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
neurobiology,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
ASH1 (absent small and homeotic disks protein 1 homolog) is a member of the trithorax group of transcriptional activators. ASH1 exhibits histone methyltransferase activity and has been observed to associate with the transcribed region of most active genes.
UniGene ID
Hs.491060
UniProt ID (eCommerce)
Q9NR48

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.