human ASB2 shRNA silencing Adenovirus

Name
Ad-h-ASB2-shRNA

Cat No
shADV-201529

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ASB2.

shADV-201529

Ad-h-ASB2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ASB2 (ankyrin repeat and SOCS box containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ASB-2

Description (Vector)

ASB2 encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. ASB2 plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

51676

Gene Name (Vector)

ankyrin repeat and SOCS box containing 2

Gene Symbol

ASB2

HGNC ID

HGNC:16012

ORF Size (aa)

1764

ORF Size (bp)

1764 bp

RefSeq ID

NM_016150

RefSeq Synonyms

NM_016150, NM_001202429, BC032354,

Species

human

UniGene ID

Hs.510327

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.