human ASAP3 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ASAP3

Gene Name

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

Gene ID

55616

Gene Synonyms

ACAP4; CENTB6; DDEFL1; UPLC1

ORF Size

2712 bp

RefSeq#

NM_017707

Gene Description

ASAP3 encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.437379

HGNC ID

HGNC:14987