human ARHGEF15 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ARHGEF15.
shADV-201358
Ad-h-ARHGEF15-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ARHGEF15 (Rho guanine nucleotide exchange factor 15). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARGEF15; E5; Ephexin5; Vsm-RhoGEF
Description (Vector)
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.
Gene ID
22899
Gene Name (Vector)
Rho guanine nucleotide exchange factor 15
Gene Symbol
ARHGEF15
HGNC ID
HGNC:15590
ORF Size (aa)
2526
ORF Size (bp)
2526 bp
RefSeq ID
NM_173728
RefSeq Synonyms
NM_173728, NM_025014, BC036749,
Species
human
UniGene ID
Hs.443109
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.