human AP3M1 shRNA silencing Adenovirus

Name 
Ad-h-AP3M1-shRNA
Cat No 
shADV-201101
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human AP3M1.

shADV-201101
Ad-h-AP3M1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AP3M1 (adaptor related protein complex 3 mu 1 subunit). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
AP3M1 is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.
Gene ID
26985
Gene Name (Vector)
adaptor related protein complex 3 mu 1 subunit
Gene Symbol
AP3M1
HGNC ID
HGNC:569
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
RefSeq ID
NM_012095
RefSeq Synonyms
NM_207012, NM_012095, NM_001320265, NM_001320264, NM_001320263, BC067127, BC026232,
Species
human
UniGene ID
Hs.500104

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.