human AP1S1 shRNA silencing Adenovirus

Name 
Ad-h-AP1S1-shRNA
Cat No 
shADV-201084
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human AP1S1.

shADV-201084
Ad-h-AP1S1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AP1S1 (adaptor related protein complex 1 sigma 1 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
adapter-related protein complex 1 sigma-1A subunit; adaptor protein complex AP-1 subunit sigma-1A; adaptor related protein complex 1 sigma 1 subunit; adaptor-related protein complex 1 subunit sigma-1A; AP-1 complex subunit sigma-1A; AP19; CLAPS1; clathrin assembly protein complex 1 sigma-1A small chain; clathrin coat assembly protein AP19; clathrin-associated/assembly/adaptor protein, small 1 (19kD); EKV3; golgi adaptor HA1/AP1 adaptin sigma-1A subunit; HA1 19 kDa subunit; MEDNIK; Sigma 1a subunit of AP-1 clathrin; SIGMA1A; sigma1A subunit of AP-1 clathrin adaptor complex; sigma1A-adaptin; Sigma-adaptin 1A
Description (eCommerce)
AP-1 complex subunit sigma-1A (AP1S1) is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle [taken from NCBI Entrez Gene (Gene ID: 1174)].
Description (Vector)
AP1S1 is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle.
Gene ID
1174
Gene Name (eCommerce)
adaptor related protein complex 1 subunit sigma 1
Gene Name (Vector)
adaptor related protein complex 1 sigma 1 subunit
Gene Symbol
AP1S1
HGNC ID
HGNC:559
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
402
ORF Size (bp)
402 bp
Protein Name (eCommerce)
AP-1 complex subunit sigma-1A
RefSeq ID
NM_001283
RefSeq Synonyms
NM_001283, BC003561,
Research Areas
Antigen Processing and Presentation,Golgi Apparatus,Host-Virus Interactions,Immunology,Lysosome,Neurobiology,Neurodevelopment,Response to Virus
Research Areas (Faceted)
immunology,cell_biology,neurobiology,developmental_biology,infectious_disease
Species
human
Target Sentence
AP-1 complex subunit sigma-1A (AP1S1) is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle [taken from NCBI Entrez Gene (Gene ID: 1174)].
UniGene ID
Hs.718546
UniProt ID (eCommerce)
P61966

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.