human ALOX5AP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ALOX5AP.
shADV-200805
Ad-h-ALOX5AP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ALOX5AP (arachidonate 5-lipoxygenase activating protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FLAP
Description (Vector)
ALOX5AP encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene ID
241
Gene Name (Vector)
arachidonate 5-lipoxygenase activating protein
Gene Symbol
ALOX5AP
HGNC ID
HGNC:436
ORF Size (aa)
486
ORF Size (bp)
486 bp
RefSeq ID
NM_001629
RefSeq Synonyms
NM_001629, NM_001204406, BC018538,
Species
human
UniGene ID
Hs.507658
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.