human ALDH6A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ALDH6A1.
shADV-200744
Ad-h-ALDH6A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ALDH6A1 (aldehyde dehydrogenase 6 family member A1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MMSADHA; MMSDH
Description (Vector)
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Gene ID
4329
Gene Name (Vector)
aldehyde dehydrogenase 6 family member A1
Gene Symbol
ALDH6A1
HGNC ID
HGNC:7179
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_005589
RefSeq Synonyms
NM_005589, NM_001278594, NM_001278593, BC032371, BC004909,
Species
human
UniGene ID
Hs.293970
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.