human AK3L1 shRNA silencing Adenovirus

Name 
Ad-h-AK3L1-shRNA
Cat No 
shADV-200640
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human AK4.

shADV-200640
Ad-h-AK3L1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AK4 (adenylate kinase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AK 4; AK3; AK3L1; AK3L2
Description (Vector)
AK4 encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
Gene ID
205
Gene Name (Vector)
adenylate kinase 4
Gene Symbol
AK4
HGNC ID
HGNC:363
ORF Size (aa)
672
ORF Size (bp)
672 bp
RefSeq ID
NM_013410
RefSeq Synonyms
NM_203464, NM_013410, NM_001330616, NM_001005353, BC148270, BC146653, BC136887, BC136886, BC066944, BC040224, BC016180,
Species
human
UniGene ID
Hs.592601

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.