human AIP shRNA silencing Adenovirus

Name 
Ad-h-AIP-shRNA
Cat No 
shADV-200628
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human AIP.

shADV-200628
Ad-h-AIP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AIP (aryl hydrocarbon receptor interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AH receptor-interacting protein; AIP; ARA9; Aryl-hydrocarbon receptor-interacting protein; FKBP16; FKBP37; HBV X-associated protein 2; immunophilin homolog ARA9; PITA1; SMTPHN; XAP2; XAP-2
Description (eCommerce)
Aryl hydrocarbon receptor interacting protein (AIP) is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. AIP is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP can regulate the expression of many xenobiotic metabolizing enzymes and can bind specifically to and inhibit the activity of hepatitis B virus [taken from NCBI Entrez Gene (Gene ID: 9049)].
Description (Vector)
AIP is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
Gene ID
9049
Gene Name (eCommerce)
aryl hydrocarbon receptor interacting protein
Gene Name (Vector)
aryl hydrocarbon receptor interacting protein
Gene Symbol
AIP
HGNC ID
HGNC:358
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
993
ORF Size (bp)
993 bp
Protein Name (eCommerce)
AH receptor-interacting protein
RefSeq ID
NM_003977
RefSeq Synonyms
NM_003977, NM_001302960, NM_001302959, BC104827, BC104797,
Research Areas
Protein Folding,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Aryl hydrocarbon receptor interacting protein (AIP) is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. AIP is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP can regulate the expression of many xenobiotic metabolizing enzymes and can bind specifically to and inhibit the activity of hepatitis B virus [taken from NCBI Entrez Gene (Gene ID: 9049)].
UniGene ID
Hs.412433
UniProt ID (eCommerce)
O00170

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.