human AGER shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human AGER.
shADV-200552
Ad-h-AGER-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human AGER (advanced glycosylation end product-specific receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MGC22357; RAGE;
Description (Vector)
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
Gene ID
177
Gene Name (Vector)
advanced glycosylation end product-specific receptor
Gene Symbol
AGER
ORF Size (aa)
1215
ORF Size (bp)
1215 bp
RefSeq ID
NM_001136
RefSeq Synonyms
NM_172197, NM_001206966, NM_001206954, NM_001206940, NM_001206936, NM_001206934, NM_001206932, NM_001206929, NM_001136, BC020669,
Species
human
UniGene ID
Hs.534342
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.