human AES shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AES

Gene Name

amino-terminal enhancer of split

Gene ID

166

Gene Synonyms

AES-1; AES-2; ESP1; GRG; Grg-5; GRG5; TLE5

ORF Size

795 bp

RefSeq#

NM_001130

Gene Description

AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.515053

HGNC ID

HGNC:307