human ADRBK2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GRK3.
shADV-200512
Ad-h-ADRBK2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GRK3 (G protein-coupled receptor kinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADRBK2; BARK2
Description (Vector)
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
Gene ID
157
Gene Name (Vector)
G protein-coupled receptor kinase 3
Gene Symbol
GRK3
HGNC ID
HGNC:290
ORF Size (aa)
1164
RefSeq ID
NM_005160
RefSeq Synonyms
NM_005160, BC036797,
Species
human
UniGene ID
Hs.657494
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.