human ADM shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADM.
shADV-200478
Ad-h-ADM-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADM (adrenomedullin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AM; PAMP
Description (Vector)
Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
Gene ID
133
Gene Name (Vector)
adrenomedullin
Gene Symbol
ADM
HGNC ID
HGNC:259
ORF Size (aa)
558
ORF Size (bp)
558 bp
RefSeq ID
NM_001124
RefSeq Synonyms
NM_001124, BC015961,
Species
human
UniGene ID
Hs.441047
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.