human ADAMTS3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADAMTS3.
shADV-200387
Ad-h-ADAMTS3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAMTS3 (ADAM metallopeptidase with thrombospondin type 1 motif 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADAMTS-4
Description (Vector)
ADAMTS3 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.
Gene ID
9508
Gene Name (Vector)
ADAM metallopeptidase with thrombospondin type 1 motif 3
Gene Symbol
ADAMTS3
HGNC ID
HGNC:219
ORF Size (aa)
3618
ORF Size (bp)
3618 bp
RefSeq ID
NM_014243
RefSeq Synonyms
NM_014243, BC132735, BC130287,
Species
human
UniGene ID
Hs.590919
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.