human ADAMTS14 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADAMTS14.
shADV-200380
Ad-h-ADAMTS14-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAMTS14 (ADAM metallopeptidase with thrombospondin type 1 motif 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
ADAMTS14 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS14 is highly similar to two family members, ADAMTS2 and ADAMTS3, in its sequence and gene structure, and the encoded protein shares the aminoprocollagen peptidase activity with the protein products encoded by ADAMTS2 and ADAMTS3. Various transcript variants of this gene have been identified. They result from the use of two different promoters and transcription initiation sites as well as alternative splicing sites. The full length nature of some transcripts has not been defined.
Gene ID
140766
Gene Name (Vector)
ADAM metallopeptidase with thrombospondin type 1 motif 14
Gene Symbol
ADAMTS14
HGNC ID
HGNC:14899
ORF Size (aa)
3678
ORF Size (bp)
3678 bp
RefSeq ID
NM_080722
RefSeq Synonyms
NM_139155, NM_080722, BC140263,
Species
human
UniGene ID
Hs.352156
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.