human ADAMTS12 shRNA silencing Adenovirus

Name 
Ad-h-ADAMTS12-shRNA
Cat No 
shADV-200378
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ADAMTS12.

shADV-200378
Ad-h-ADAMTS12-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PRO4389
Description (Vector)
ADAMTS12 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.
Gene ID
81792
Gene Name (Vector)
ADAM metallopeptidase with thrombospondin type 1 motif 12
Gene Symbol
ADAMTS12
HGNC ID
HGNC:14605
ORF Size (aa)
4530
ORF Size (bp)
4530 bp
RefSeq ID
NM_030955
RefSeq Synonyms
NM_030955, NM_001324512, NM_001324511, BC131733, BC058841,
Species
human
UniGene ID
Hs.12680

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.