human ADAM8 shRNA silencing Adenovirus

Name 
Ad-h-ADAM8-shRNA
Cat No 
shADV-200371
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ADAM8.

shADV-200371
Ad-h-ADAM8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAM8 (ADAM metallopeptidase domain 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD156; CD156a; MS2
Description (Vector)
ADAM8 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
Gene ID
101
Gene Name (Vector)
ADAM metallopeptidase domain 8
Gene Symbol
ADAM8
HGNC ID
HGNC:215
ORF Size (aa)
2475
ORF Size (bp)
2475 bp
RefSeq ID
NM_001109
RefSeq Synonyms
NM_001164490, NM_001164489, NM_001109, BC115404,
Species
human
UniGene ID
Hs.501574

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.