human ADAM15 shRNA silencing Adenovirus

Name 
Ad-h-ADAM15-shRNA
Cat No 
shADV-200348
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ADAM15.

shADV-200348
Ad-h-ADAM15-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAM15 (ADAM metallopeptidase domain 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MDC15
Description (Vector)
ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene ID
8751
Gene Name (Vector)
ADAM metallopeptidase domain 15
Gene Symbol
ADAM15
HGNC ID
HGNC:193
ORF Size (aa)
2445
ORF Size (bp)
2445 bp
RefSeq ID
NM_003815
RefSeq Synonyms
NM_207197, NM_207196, NM_207195, NM_207194, NM_207191, NM_003815, NM_001261466, NM_001261465, NM_001261464, BC014566,
Species
human
UniGene ID
Hs.312098

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.