human ADAM11 shRNA silencing Adenovirus

Name
Ad-h-ADAM11-shRNA

Cat No
shADV-200346

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ADAM11.

shADV-200346

Ad-h-ADAM11-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADAM11 (ADAM metallopeptidase domain 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

MDC

Description (Vector)

ADAM11 encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM11 represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.

Gene ID

4185

Gene Name (Vector)

ADAM metallopeptidase domain 11

Gene Symbol

ADAM11

HGNC ID

HGNC:189

ORF Size (aa)

2307

ORF Size (bp)

2307 bp

RefSeq ID

NM_002390

RefSeq Synonyms

NM_002390, NM_001318933, BC111916,

Species

human

UniGene ID

Hs.6088

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.